制霉菌素 T1678
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1400-61-9 | ¥185.00 | 询底价 |
500 mg | 1400-61-9 | ¥413.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Nystatin
描述: Nystatin (Fungicidin) 是一种口服对酵母和支原体有效的多烯类抗真菌抗生素。它能增加质膜对包括氯离子等小单价离子的通透性。它可部分阻止 Oxaliplatin 诱导的脂筏聚集、DR4 和 DR5 聚集的胆固醇隔离试剂,减少细胞凋亡。
体内活性: Nystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues rather than in normal tissues of tumor-bearing mice, ultimately leading to elevated antiangiogenic and antitumor efficacies of endostatin in vivo[3]. Liposomal Nystatin, at doses as low as 2 mg/kg of body weight/day, protects neutropenic mice against Aspergillus-induced death in a statistically significant manner at the 50-day time point compared to either the no-treatment, the saline, or the empty-liposome group[4].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (53.99 mM)
5% DMSO+95% Saline : 0.95 mg/mL (1.03 mM, suspension)
关键字: Fungal | Inhibitor | Apoptosis | inhibit | Antibiotic | Nystatin
相关产品: TVB-3166 | Ciglitazone | MitoBloCK-6 | Flurochloridone | INH6 | PI-273 | NSC 15364 | PRIMA-1 | Phenoxodiol | Iberdomide
相关库: Drug Repurposing Compound Library | Approved Drug Library | Bioactive Compounds Library Max | Macrocyclic Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途