化合物 T16900 T16900

Product Introduction
Bioactivity


英文名: SMER18

描述: SMER18 is a small molecule enhancer of rapamycin which acts as an mTOR-independent autophagy inducer.

体外活性: SMER18 acts either independently or downstream of the target of Rapamycin, attenuates mutant huntingtin-fragment toxicity in Huntington's disease cell and Drosophila melanogaster models. mTOR SMER18 induces autophagy independently of Rapamycin in mammalian cells, enhancing the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein, which are associated with Huntington's disease and familial Parkinson's disease, respectively.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: SMER18 | SMER-18 | SMER 18

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途