化合物SP187 T16914
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 615253-61-7 | ¥2,490.00 | 询底价 |
10 mg | 615253-61-7 | ¥6,880.00 | 询底价 |
100 mg | 615253-61-7 | ¥18,600.00 | 询底价 |
5 mg | 615253-61-7 | ¥4,990.00 | 询底价 |
50 mg | 615253-61-7 | ¥13,800.00 | 询底价 |
25 mg | 615253-61-7 | ¥9,870.00 | 询底价 |
1 mL | 615253-61-7 | ¥5,490.00 | 询底价 |
Product Introduction
Bioactivity
英文名: SP187
描述: SP187 (MON-DNJ) 是一种靶向作用于宿主的亚氨基糖。它具有抗丝状病毒感染活性。SP187可用于治疗抗流感和登革热病毒。
体外活性: SP187 (UV-4) is evaluated in vitro for its antiviral efficacy against EBOV and MARV using a yield-plaque assay format. SP187 demonstrates antiviral activity with IC50 values of 29.97 μM and 47.72 μM against EBOV and MARV, respectively.[1]
体内活性: In this study, C57Bl/6 mice are administered 10 or 100 mg/kg of SP187 or UV-5 via oral gavage or IP injection. Dosing started ~1h before infection with ~1000 pfu of mouse-adapted EBOV and is repeated BID for 10 days at approximately 12-hour intervals for UV-5 or TID at approximately 8-hour intervals for SP187. The selected doses and schedules are based on tolerability studies in naïve mice. No efficacy is observed in the iminosugar-treated mice as compared to the vehicle control.[1]
存储条件: keep away from direct sunlight,store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 63.89 mg/mL (200 mM)
关键字: UV-4 | SP 187 | MON-DNJ | SP187 | UV 4 | SP-187
相关产品: (Rac)-Golgicide A | Vorinostat | Foscarnet sodium | SARS-CoV-2 3CLpro-IN-15 | Phenytoin sodium | Brequinar | N-Desmethylclozapine | Flaviviruses-IN-2 | L-Lysine | Trachelogenin
相关库: Bioactive Compounds Library Max | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途