化合物STK16-IN-1 T16944
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 1223001-53-3 | ¥1,780.00 | 询底价 |
2 mg | 1223001-53-3 | ¥197.00 | 询底价 |
1 mL | 1223001-53-3 | ¥353.00 | 询底价 |
1 mg | 1223001-53-3 | ¥139.00 | 询底价 |
5 mg | 1223001-53-3 | ¥322.00 | 询底价 |
10 mg | 1223001-53-3 | ¥571.00 | 询底价 |
25 mg | 1223001-53-3 | ¥1,190.00 | 询底价 |
100 mg | 1223001-53-3 | ¥2,570.00 | 询底价 |
Product Introduction
Bioactivity
英文名: STK16-IN-1
描述: STK16-IN-1是一种STK16激酶抑制剂(IC50:295 nM)。
体外活性: STK16-IN-1 inhibits mTOR kinase (IC50: 5.56 μM). STK16-IN-1 shows potent inhibitory activity against STK16 kinase (IC50=0.295 μM) with excellent selective across the kinome as assessed using the KinomeScanTM profiling assay. STK16-IN-1 treatment causes a reduction in cell number and accumulation of binucleated cells, which can be recapitulated by RNAi knockdown of STK16 in MCF-7 cells. Co-treatment of STK16-IN-1 with chemotherapeutics such as cisplatin, doxorubicin, colchicine and paclitaxel results in a slight potentiation of the anti-proliferative effects of the chemotherapeutics. STK16-IN-1 provides a useful tool compound for further elucidating the biological functions of STK16) [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 15 mg/mL (51.14 mM)
关键字: STK16-IN-1 | STK16IN1 | STK-16-IN-1 | Inhibitor | STK16 IN 1 | inhibit
相关库: Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途