托瑞司他 T17114
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 82964-04-3 | ¥993.00 | 询底价 |
50 mg | 82964-04-3 | 面议 | 询底价 |
1 mg | 82964-04-3 | ¥448.00 | 询底价 |
2 mg | 82964-04-3 | ¥628.00 | 询底价 |
10 mg | 82964-04-3 | ¥1,570.00 | 询底价 |
1 mL | 82964-04-3 | ¥1,090.00 | 询底价 |
25 mg | 82964-04-3 | ¥3,290.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Tolrestat
描述: Tolrestat (AY-27773) 是一种口服有效的醛糖还原酶抑制剂 (IC50 = 35 nM)。
体内活性: The estimated ID in the sciatic nerve and lenses is 4.8 and about 20 for tolrestat, and 1.7 and 2.2 for (±)sorbinil, respectively in diabetic rats[1]. Tolrestat inhibits tissue AR activity but does not significantly affect plasma lipoprotein levels, or affect the body weight of the mice or their general health. Accumulation of cholesterol-rich foam cells is significantly increased in aortic roots of tolrestat-fed mice[2]. Tolrestat (1.8 mg/kg) causes a reversal of normal RBC sorbitol levels[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 100 mg/mL (279.84 mM)
关键字: Inhibitor | inhibit | AY27773 | Tolrestat | AY 27773 | Aldose Reductase
相关产品: Turosteride | Quercetin 3-gentiobioside | Ponalrestat | 8-Lavandulylkaempferol | Alrestatin | Aldose reductase-IN-1 | 2'-acetylacteoside | Engeletin | Izonsteride | Fidarestat
相关库: ReFRAME Related Library | Drug-induced Liver Injury (DILI) Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Metabolism Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途