氨氟沙星 T17254

Product Introduction
Bioactivity


英文名: Amifloxacin

描述: Amifloxacin (Win49375) 是有效的喹诺酮类抗菌剂。

体外活性: The activity of Amifloxacin in vitro was comparable to those of norfloxacin and pefloxacin against Enterobacteriaceae and generally greater than those of tobramycin and cefotaxime. Amifloxacin was more active in vitro than carbenicillin and mezlocillin against Pseudomonas aeruginosa isolates[1].

体内活性: Against systemic, gram-negative bacterial infections in mice, Amifloxacin was generally less active than cefotaxime but more active than gentamicin. WIN 49548, the major piperazinyl-N-desmethyl metabolite of Amifloxacin, was aa effective as the parent drug against experimental infections in mice when given parenterally. When administered orally, however, this metabolite was less potent than Amifloxacin. Amifloxacin was highly active by the oral route, with 50% effective doses within two- to threefold of those obtained with parenteral medication[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 4 mg/ml (11.96 mM)


关键字: Inhibitor | Amifloxacin | Win-49375 | inhibit | Win 49375 | Bacterial

相关产品: Esculin | Saccharin | Betamipron | Tunicamycin | Clofazimine | Luciferase-IN-1 | Vasicine hydrochloride | Tebipenem Pivoxil | ANT3310 | Rimonabant hydrochloride

相关库: ReFRAME Related Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Bacterial Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途