化合物(S,R,S)-AHPC-PEG3-N3 T17909

Product Introduction
Bioactivity


英文名: (S,R,S)-AHPC-PEG3-N3

描述: (S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。

体外活性: (S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1, figure 11. PROTAC has been developed with an A-L-B structure that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compound via a suitable linker[1][2].

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (77.43 mM)


关键字: (S,R,S) AHPC PEG3 N3 | (S,R,S)-AHPC-PEG-3-N3 | Inhibitor | inhibit | E3 Ligase Ligand-Linker Conjugates | AHPC-PEG3-N3 | (S,R,S)AHPCPEG3N3

相关产品: Thalidomide-O-amido-C3-NH2 TFA | Avadomide | CC-885 | Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride | CRBN modulator-1 | (S,R,S)-AHPC-PEG4-NH2 | Thalidomide-propargyl | Thalidomide-NH-C4-NH-Boc | Thalidomide-O-amido-PEG3-C2-NH2 TFA | Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途