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其他生物化学试剂

化合物 T19042 T19042

英文名称:NucPE1
品牌 厂商性质 产地 货期
TargetMol 生产商 美国 现货

性能特点

生化试剂,可用于动物细胞实验

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产品参数
规格 CAS号 价格 操作
10 mg 1404091-23-1 ¥6,230.00 询底价
5 mg 1404091-23-1 ¥3,730.00 询底价
产品介绍

Product Introduction
Bioactivity


英文名: NucPE1

描述: NucPE1, a nuclear-localized fluorescent hydrogen peroxide, is specifically localized to cellular nuclei without appended targeting moieties.

体外活性: NucPE1 features two major visible region absorptions (λabs=468 nm, ε=27,300 M-1cm-1; λabs=490 nm, ε=26,000 /(M·cm)) and a weak emission (λem=530 nm, Φ=0.117). Reaction of NucPE1 with H2O2 triggers a fluorescence increase upon its conversion to fluorophore NucPE1, which possesses one major absorption band at 505 nm (ε=19,100 /(M·cm)) with enhanced emission (λem=530 nm, Φ=0.626). NucPE1 selectively accumulates in the nuclei of a variety of mammalian cell lines as well as in whole model organisms like C. clegans, where it can respond to subcellular changes in H2O2 fluxes.

体内活性: NucPE1 imaging reveals a reduction in nuclear H2O2 levels in worms overexpressing sir-2.1 compared to wildtype congeners.

存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 25 mg/mL (51.72 mM)


关键字: NucPE-1 | NucPE1

化合物 T19042 T19042信息由TargetMol中国为您提供,如您想了解更多关于化合物 T19042 T19042报价、型号、参数等信息,欢迎来电或留言咨询。

注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途

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