二十二碳四烯酸 T19180

Product Introduction
Bioactivity


英文名: Adrenic Acid

描述: Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) 是一种天然的多不饱和脂肪酸，主要存在于肾上腺，肾脏，大脑和脉管系统中。Adrenic Acid 能够调节肾上腺皮质血管的血管紧张度。Adrenic Acid 也是非酒精性脂肪肝疾病的炎症增强剂。

体外活性: The hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). The hepatic and plasma levels of Adrenic Acid exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 8 mg/mL (24.06 mM)


关键字: Endogenous Metabolite | vascular | Inhibitor | fatty | polyunsaturated | inflammation | inhibit | Adrenic Acid

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相关库: Human Endogenous Metabolite Library | Bioactive Compounds Library Max | Human Metabolite Library | Human Endogenous Metabolite Compound Library Plus | Natural Product Library for HTS | Gut Microbial Metabolite Library | NO PAINS Compound Library | Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途