二噻农 T19285

Product Introduction
Bioactivity


英文名: Dithianon

描述: Dithianon is a broad-spectrum anthraquinone fungicide with good adhesion to the surface of leaves and fruits. Dithianon can be used to control several fungi in certain fruits and vegetables.

体外活性: When Saccharomyces cerevisiae aerobic growth index cells are treated with acute dithione, they lose cell wall and membrane integrity and die from necrosis, and this behavior is related to the reduction of protein and non-protein sulfhydryl groups. A large increase in cellular reactive oxygen species (ROS) associated with mitochondrial membrane potential modification in cells treated with Dithianon was also detected. In filamentous fungi, Dithianon inhibits mycelial growth and conidial germination. Studies on Ehrlich ascites carcinoma and yeast cells have shown that Dithianon inhibits respiration and fermentation and affects several thiol enzymes in the glycolysis pathway, such as hexokinase, phosphofructokinase, and glycoeraldeyde-3-phosphate dehydrogenase. Dithianon has cytotoxicity in vitro and affects the cell transformation activity of BLAB/c 3 T3 cells.

体内活性: The activity of testosterone hydroxylase in liver microsomes of male mice increases after acute doses of Dithianon treatment, while female mice show inactivation.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Dithianon

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途