化合物Solutol HS-15 T19562

Product Introduction
Bioactivity


英文名: Polyethylene glycol 12-hydroxystearate

描述: Polyethylene glycol 12-hydroxystearate (Solutol HS-15) 是一种通透性增强剂，是一种 Macrogol 15 羟基硬脂酸酯。

体外活性: Solutol HS-15 promotes the apical-to-basolateral translocation of a model protein (insulin) across Calu-3 monolayers when applied at 37°C. Furthermore there is no statistically significant increase in insulin permeability in the presence of Solutol HS-15, relative to the respective control, at 4°C. Solutol HS-15 treated cells show a statistically significant increase in permeability towards lower molecular weight permeants (5 to 22 kDa) and an absence of a statistically significant increase in permeability of proteins with larger molecular weight, namely albumin and IgG (P>0.05 relative to control).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 100 mg/mL
H2O : 25 mg/mL


关键字: Polyethylene glycol 12-hydroxystearate | Inhibitor | inhibit | Solutol | Polyethylene glycol 12 hydroxystearate | Polyethylene glycol 12hydroxystearate | HS-15

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途