2-氟腺嘌呤 T20038

Product Introduction
Bioactivity


英文名: 2-Fluoroadenine

描述: 2-Fluoroadenine (NSC-27364) 对非增殖性和增殖性肿瘤细胞具有毒性。2-Fluoroadenine 可用于抗癌症的相关研究。

体外活性: In Balb-3T3 cells, 2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses. In CEM cells, 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis. In nonproliferating MRC-5 cells, 2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 4.4 mg/mL (26.97 mM)


关键字: CEM | Purine bases | Cytotoxicity | MRC-5 | Anticancer | DNA/RNA Synthesis | Inhibitor | 2-Fluoroadenine | 2 Fluoroadenine | inhibit | 2Fluoroadenine

相关产品: PU-H71 HCl | Ancitabine hydrochloride | Tegafur | Isoindigotin | Triazavirin | β-Boswellic acid | Deoxycytidine triphosphate trisodium salt | Kukoamine A | α-​Chaconine | L67

相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Cancer Active Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途