头孢西丁 T20643

Product Introduction
Bioactivity


英文名: Cefoxitin

描述: Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌，通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部，对厌氧菌具有高效性。

体外活性: Cefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL[1].Cefoxitin (1.25 µM/mL) exhibits high efficacy killing B. burgdorferi at concentration [2].

体内活性: 给予C3H/HeN小鼠模型每天通过腹腔注射方式连续5天使用20 mg/kg剂量的Cefoxitin，有效根除了B. burgdorferi。[2]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 90.0 mg/mL (210.6 mM)


关键字: Cefoxitin

相关产品: Colistin sulfate | Vancomycin hydrochloride | Colistin methanesulfonate sodium salt | Isoxaben | Carbenicillin disodium | Chlorhexidine dihydrochloride

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Approved Drug Library | Bioactive Compounds Library Max | Natural Product Library for HTS | EMA Approved Drug Library | Microbial Natural Product Library | Covalent Inhibitor Library | Anti-infective Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途