化合物SBI-0206965 T2128
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 1884220-36-3 | ¥656.00 | 询底价 |
10 mg | 1884220-36-3 | ¥1,730.00 | 询底价 |
1 mL | 1884220-36-3 | ¥1,180.00 | 询底价 |
50 mg | 1884220-36-3 | ¥4,360.00 | 询底价 |
5 mg | 1884220-36-3 | ¥997.00 | 询底价 |
25 mg | 1884220-36-3 | ¥2,950.00 | 询底价 |
1 mg | 1884220-36-3 | ¥447.00 | 询底价 |
100 mg | 1884220-36-3 | ¥6,190.00 | 询底价 |
Product Introduction
Bioactivity
英文名: SBI-0206965
描述: SBI-0206965 是一种强效,选择性和细胞渗透性自噬激酶ULK1抑制剂,对 ULK1 激酶活性的 IC50 为 108 nM,对 ULK2 的 IC50 为 711 nM。
体外活性: In HEK293T transfected with WT or KI Myc-tagged ULK1 and WT Vps34, SBI-0206965 inhibits Ser249 phosphorylation of overexpressed Vps34 and Beclin1 Ser15 phosphorylation. SBI-0206965 suppresses autophagy induced by mTOR inhibition in A549 cells, and prevents ULK1-dependent cell survival in WT MEFs. In addition, SBI-0206965 also synergizes with mTOR inhibition to induce cancer cell death. [1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 20 mg/mL
关键字: SBI 0206965 | inhibit | Inhibitor | Unc-51 like kinase | Apoptosis | Autophagy | SBI-0206965 | ULK
相关产品: Soyasapogenol B | TCS7010 | trans-Chalcone | Minodronic acid | Deferoxamine | Limonin | CPI-360 | Tasisulam | Ro 90-7501 | RGD peptide (GRGDNP)
相关库: Anti-Aging Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | Highly Selective Inhibitor Library | Apoptosis Compound Library | Autophagy Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Bioactive Compound Library
化合物SBI-0206965 T2128信息由TargetMol中国为您提供,如您想了解更多关于化合物SBI-0206965 T2128报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途