盐酸阿替卡因 T2131
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 23964-57-0 | ¥198.00 | 询底价 |
25 mg | 23964-57-0 | ¥340.00 | 询底价 |
50 mg | 23964-57-0 | ¥480.00 | 询底价 |
200 mg | 23964-57-0 | ¥1,150.00 | 询底价 |
500 mg | 23964-57-0 | ¥1,950.00 | 询底价 |
100 mg | 23964-57-0 | ¥785.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Articaine hydrochloride
描述: Articaine hydrochloride (Hoe-045) 一种牙科局部麻醉剂。
体内活性: The time to maximum drug concentrations of articaine occurs about 10 to 15 minutes after submucosal injection of articaine 4% 80 mg. The elimination half-time of articaine is about 20 minutes. Articaine is better able to diffuse through soft tissue and bone than other local anaesthetics, the concentration of articaine in the alveolus of a tooth in the upper jaw after extraction is about 100 times higher than that in systemic circulation. [1] Articaine: VAS (Visual Analogue Scale) scores (from 0 to 10 cm) by patients 4 to < 13 years of age are 0.5 for simple procedures and 1.1 for complex procedures, and average investigator scores are 0.4 and 0.6 for simple and complex procedures, respectively. No serious adverse events related to the articaine occurres, the only adverse event considered related to articaine is accidental lip injury in one patient. [2] Articaine results in success rate of 64.5% in electronic pulp testing in healthy adult volunteers injected with 4% articaine. Articaine infiltration produces significantly more episodes of no response to maximum stimulation in first molars than lidocaine. Mandibular buccal infiltration is more effective with 4% articaine with epinephrine compared to 2% lidocaine with epinephrine. [3] Articaine (4%) results in the success rate of 24% for the inferior alveolar nerve block in randomized, double-blind study. [4] Articaine formulation results in successful pulpal anesthesia ranged from 75 to 92 percent and onset of pulpal anesthesia ranged from 4.2 to 4.7 minutes in healthy volunteer. For articaine, 4 percent (two of 56) of the subjects reported swelling and no subjects reported bruising. Ninety-eight percent (59 of 60) of the subjects had lip numbness with the articaine solution. [5]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 60 mg/mL (187.01 mM)
H2O : 59 mg/mL (183.9 mM)
Ethanol : 60 mg/mL (187 mM)
关键字: dental | Articaine | Articaine Hydrochloride | NOD-like Receptor (NLR) | Hoe 045 | amide | pain relief | Hoe045 | Sodium Channel | inhibit | Na channels | kidney injury | Nuclear factor-κB | LPS | NF-κB | Na+ channels | Articaine hydrochloride | Nuclear factor-kappaB | Inhibitor
相关产品: Rimeporide | Ropivacaine hydrochloride | Procaine hydrochloride | Scorpion toxin Tf2 | Odoroside H | PF-06869206 | (5R)-BW-4030W92 | 6-Iodoamiloride | Prilocaine hydrochloride | Pilsicainide HCl
相关库: Ion Channel Inhibitor Library | Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | Sodium Channel Blocker Library | NO PAINS Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途