尿苷三乙酸酯 T21327
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 4105-38-8 | ¥359.00 | 询底价 |
1 g | 4105-38-8 | ¥518.00 | 询底价 |
100 mg | 4105-38-8 | ¥163.00 | 询底价 |
5 g | 4105-38-8 | ¥1,260.00 | 询底价 |
200 mg | 4105-38-8 | ¥226.00 | 询底价 |
1 mL | 4105-38-8 | ¥179.00 | 询底价 |
50 mg | 4105-38-8 | ¥123.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Uridine triacetate
描述: Uridine triacetate (RG 2133 triacetate) 是一种具有口服活性的 Uridine 前药。Uridine triacetate 能在肠道内迅速被吸收,在循环中迅速脱乙酰,生成游离尿苷。Uridine triacetate 可用于研究 5-氟尿嘧啶 (5-FU) 和卡培他滨的毒性,或早发性心脏或中枢神经系统 (CNS) 毒性。
体外活性: Uridine triacetate inhibits [3H]uridine uptake in ENT1 and ENT2 overexpressed HeLa cells, with IC50s of 28.4 μM and 228.4 μM respectively[4].
体内活性: Uridine triacetate (2 g/kg, oral gavage, every 8 h for 15 total doses) improves survival and reduced toxicity in 5-FU overdose mice. Uridine triacetate (2 g/kg, oral gavage, every 8 h for 15 total doses) improves survival and reduced 5-FU toxicity in DPD deficiency mice[3].
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : Insoluble
DMSO : 90mg/mL (243mM)
关键字: RG 2133 Triacetate | Uridine Triacetate | RG2133 Triacetate | Uridine | RG-2133 Triacetate
相关库: Nucleotide Compound Library | Drug Repurposing Compound Library | Approved Drug Library | Anti-Cancer Compound Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Clinical Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | Anti-Cancer Active Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途