化合物T21582L T21582L

Product Introduction
Bioactivity


英文名: Acetyl Angiotensinogen (1-14), porcine Acetate

描述: Acetyl Angiotensinogen (1-14), porcine Acetate 是一种肽，序列为 AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH。由血管紧张素原基因编码的蛋白质被称为前血管紧张素原或血管紧张素原前体。

体外活性: The renin-angiotensin system?was extracted from blood with 70% acetone and had a short pressor effect.?The renin acted enzymatically on a plasma protein to produce the new substance.?

体内活性: The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.?Pre-angiotensinogen is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.?The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.?Angiotensin II is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia[2].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 162mg/mL(89.95mM)


关键字: Acetyl Angiotensinogen , porcine Acetate | 66641-26-7 | 66641-26-7 Free base | Acetyl Angiotensinogen (114), porcine Acetate | Acetyl Angiotensinogen (1 14), porcine Acetate

相关库: Anti-Metabolism Disease Compound Library | Peptide Compound Library | Anti-Diabetic Compound Library | NO PAINS Compound Library

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