化合物BMS 453 T21714
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 166977-43-1 | ¥828.00 | 询底价 |
50 mg | 166977-43-1 | ¥2,920.00 | 询底价 |
100 mg | 166977-43-1 | ¥4,190.00 | 询底价 |
10 mg | 166977-43-1 | ¥1,180.00 | 询底价 |
500 mg | 166977-43-1 | 面议 | 询底价 |
25 mg | 166977-43-1 | ¥1,980.00 | 询底价 |
1 mg | 166977-43-1 | ¥287.00 | 询底价 |
5 mg | 166977-43-1 | ¥678.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BMS453
描述: BMS453 (BMS-189453) 是一种合成类维生素 A,是一种 RARβ激动剂,也是一种 RARα/RARγ拮抗剂。它主要通过诱导活性 TGFβ 来抑制乳腺细胞生长。
体外活性: BMS453 (1 μM; 11 hours; 184 and HMEC cells) treatment inhibits the proliferation of normal breast cell growth without significantly inducing apoptosis[2].The RARβ-selective agonist (BMS453), but not RARα- or RARγ-selective agonists (BMS753 and BMS961, respectively), significantly reduced the T47D breast cancer cell migration to levels comparable to inhibition by RA, indicating that RARβ is involved in RA-inhibited cell migration[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 45 mg/mL (118.27 mM)
关键字: Inhibitor | retinoid | BMS-453 | RAR/RXR | BMS453 | inhibit | BMS189453 | TGFβ | breast | RARβ | RARγ | Retinoid X receptors | arrest | cell | RARα | BMS 189453 | Retinoic acid receptors
相关产品: CD2665 | Tarenflurbil | palovarotene | PA452 | Magnolol | CD 1530 | Peretinoin | Isotretinoin | MSU-42011 | WYC-209
相关库: Neuronal Differentiation Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Nuclear Receptor Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途