化合物BR-1 T22136

Product Introduction
Bioactivity


英文名: PRL-3 Inhibitor I

描述: PRL-3 Inhibitor I (BR-1) 是 PRL-3 抑制剂，IC50=0.9 μM。它在细胞检测中显示降低侵袭性。

体外活性: PRL-3 inhibitor, in a dose-dependent fashion, blocked the dephosphorylation of DiFMUP by PRL-3 and strongly suppressed the activity of PRL-3 phosphatase in PRL-3 overexpressing DLD-1 colon tumor cells [DLD-1 (PRL-3)]. Also, PRL-3 inhibitor dose-dependently blocked the migration of DLD-1 (PRL-3) cells, however, it did not inhibit the proliferation of DLD-1(PRL-3) cells, suggesting that PRL-3 inhibitor significantly blocked cell immigration and invasion without cytotoxicity

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (113.35 mM)


关键字: cells | Inhibitor | PRL3 Inhibitor I | invasion | BR 1 | BR1 | inhibit | melanoma | PRL 3 Inhibitor I | B16F10 | PRL-3 Inhibitor I | Phosphatase

相关产品: L-Ascorbic acid 2-phosphate magnesium | LMPTP INHIBITOR 1 hydrochloride | h-NTPDase-IN-3 | LUPENONE | Sodium metatungstate | NSC 65809 | PTP1B/AKR1B1-IN-1 | 1-Naphthyl phosphate potassium salt | Disodium monofluorophosphate | Ebselen

相关库: Glycometabolism Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Phosphatase Inhibitor Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途