1-甘露糖野尻霉素盐酸盐 T22468

Product Introduction
Bioactivity


英文名: 1-Deoxymannojirimycin hydrochloride

描述: 1-Deoxymannojirimycin hydrochloride 是一种选择性的 α1,2-甘露糖苷酶抑制剂，IC50值为 20 μM。它还抑制 HIV-1 毒株，抗病毒活性较差。

体外活性: Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures[1].When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed[1].

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 20 mg/ml(100.19 mM)
H2O : 20 mg/ml(100.19 mM)


关键字: 1 Deoxymannojirimycin hydrochloride | HIV-1 | inhibit | glycosylation | antiviral | Influenza Virus | reticulum | HIV | α1,2-mannosidase | Human immunodeficiency virus | N-linked | 1-Deoxymannojirimycin Hydrochloride | Inhibitor | 1Deoxymannojirimycin hydrochloride | 1-Deoxymannojirimycin | Endoplasmic

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