化合物 T22676 T22676
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | T22676 | ¥393.00 | 询底价 |
10 mg | T22676 | ¥1,833.00 | 询底价 |
5 mg | T22676 | ¥1,113.00 | 询底价 |
25 mg | T22676 | ¥2,553.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Prothrombin (474-477) [Mus musculus]
描述: Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothrombin is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss.
体外活性: Activation of prothrombin is crucial in physiological and pathological coagulation. Various rare diseases involving prothrombin have been described (e.g., hypoprothrombinemia). Anti-prothrombin antibodies in autoimmune disease may be a factor in the formation of the lupus anticoagulant, also known as antiphospholipid syndrome. Hyperprothrombinemia can be caused by the G20210A mutation. Thus, manipulation of prothrombin is central to the mode of action of most anticoagulants [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : ≥52.9mg/mL
关键字: Prothrombin (474477) [Mus musculus] | Prothrombin [Mus musculus] | Prothrombin (474 477) [Mus musculus]
化合物 T22676 T22676信息由TargetMol中国为您提供,如您想了解更多关于化合物 T22676 T22676报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途