5,5-二甲基-1-吡咯啉-N-氧化物 T22739

Product Introduction
Bioactivity


英文名: DMPO

描述: DMPO (5,5-Dimethyl-1-pyrroline N-oxide) 是一种细胞渗透性亲水自旋诱捕剂，可用于超氧化物检测。

体外活性: In vitro, It was demonstrated in red blood cells and in hamster V79 cells that the DMPO spin adducts of ·O2? and ·OH are metabolized very rapidly so that even if formed, they may not be detected in many experiments with cells [1].

体内活性: When DMPO perfused the heart at 100 μm/L, it attenuated the development of reperfusion arrhythmias during the first 10 min of reperfusion and improved the functional recovery of the heart during reperfusion. Without treatment, 55% of hearts showed irreversible ventricular fibrillation, and this was completely prevented by DMPO, due to its function of traping·O2? and ·OH radicals [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (486.04 mM)


关键字: inhibit | DMPO | Inhibitor

相关库: Bioactive Compounds Library Max | Human Metabolite Library | Bioactive Compound Library

5,5-二甲基-1-吡咯啉-N-氧化物 T22739信息由TargetMol中国为您提供，如您想了解更多关于5,5-二甲基-1-吡咯啉-N-氧化物 T22739报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途