1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮 T23116

Product Introduction
Bioactivity


英文名: Oxotremorine sesquifumarate

描述: Oxotremorine sesquifumarate 是一种毒蕈碱受体激动剂，对 M2 的激活作用更强，可用于神经学研究。

体外活性: Oxotremorine (10.5 micron) produced a paralytic effect on twitch responses of rat diaphragm in vitro to direct and indirect stimulation[1].

体内活性: Rats with signs of neuropathy were subjected to SCS applied in awake, freely moving condition. Oxotremorine was administered intrathecally. Tactile, cold and heat sensitivities were assessed by using von Frey filaments, cold spray and focused radiant heat, respectively. Oxotremorine i.t. dose-dependently suppressed the tactile hypersensitivity. SCS markedly increased withdrawal thresholds (WTs), withdrawal latencies and cold scores[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : < 28 mg/mL (73.61 mM)
H2O : < 8 mg/mL (21.03 mM)


关键字: Inhibitor | mAChR | inhibit | tremorogenic | Oxotremorine sesquifumarate | neurological | Muscarinic acetylcholine receptor

相关产品: S16961 | Nitrocaramiphen hydrochloride | 7-O-Methyleriodictyol | Piperidolate | Conodurine | PNU-282987 | VU0453595 | Arecoline | GSK233705 | beta-Amyrone

相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Anti-Parkinson's Disease Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Anti-Alzheimer's Disease Compound Library | Bioactive Compound Library

1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮 T23116信息由TargetMol中国为您提供，如您想了解更多关于1-(4-[1-吡咯烷基]-2-丁炔基)-2-吡咯烷酮 T23116报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途