氯谷胺 T2312
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 107097-80-3 | ¥3,550.00 | 询底价 |
500 mg | 107097-80-3 | ¥7,890.00 | 询底价 |
1 mL | 107097-80-3 | ¥283.00 | 询底价 |
50 mg | 107097-80-3 | ¥1,820.00 | 询底价 |
5 mg | 107097-80-3 | ¥283.00 | 询底价 |
25 mg | 107097-80-3 | ¥996.00 | 询底价 |
10 mg | 107097-80-3 | ¥498.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Loxiglumide
描述: Loxiglumide (CR-1505) 是一种缩胆囊素受体拮抗剂。
激酶实验: Kinase binding assays: For optimization of Axl/TAM receptor inhibitors, an Axl binding assay is established (HTRF method; Kinase tracer 236). This assay is based on the binding and displacement of the Alexa Fluor 647-labelled Kinase tracer 236 to each glutathione S-transferase (GST)-tagged kinase used in the binding assay. Binding of the tracer to the kinase was detected by using europium (Eu)-labelled anti-GST antibodies. Simultaneous binding of both the fluorescent tracer and the Eu-labelled antibodies to the GST-tagged kinase generates a fluorescence resonance energy transfer (FRET) signal. Binding of inhibitor to the kinase competes for binding with the tracer, resulting in a loss of the FRET signal. For the assay, the compound is diluted in 20?mM HEPES, pH?8.0, 1?mM DTT, 10?mM MgCl2 and 0.01% Brij35. Then, the kinase of interest (5?nM final concentration), fluorescent tracer (15?nM final concentration) and LanthaScreen Eu-anti-GST antibody (2?nM final concentration) are mixed with the respective compound dilutions (from 5?nM to 10?μM) and incubated for 1?h. The FRET signal is quantified using an EnVision Multilabellreader 2104.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4.61 mg/mL (10 mM)
关键字: CCK Receptor | Inhibitor | Loxiglumide | CR1505 | CR 1505 | inhibit | Cholecystokinin Receptor
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途