达芦那韦 T2324

Product Introduction
Bioactivity


英文名: Darunavir

描述: Darunavir (TMC114) 是一种 HIV 蛋白酶抑制剂，用于治疗艾滋病和 HIV 感染。 由于单独使用时会出现抗病毒药物耐药性，因此与其他抗 HIV 药物联合使用。

体内活性: Vipadenant (0.3-30 mg/kg) produces a dose-dependent reduction in catalepsy. Vipadenant (10 mg/kg) does not produce any statistically significant dyskinetic episodes in 6-OHDA-lesioned rats during a 19-day dosing regimen[1]. In the mouse and rat haloperidol-induced hypolocomotion models, vipadenant has a minimum effective dose of 0.1 and 1 mg/kg, respectively. Vipadenant (3 and 10 mg/kg, p.o.) is able to increase contralateral rotations in 6-OHDA lesioned rats[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 35 mg/mL (78.14 mM)


关键字: AID | Minimal | TMC-114 | cytotoxicity | Darunavir | UIC 94017 | Human immunodeficiency virus | UIC94017 | Inhibitor | inhibit | HIV Protease | HIV | UIC-94017 | TMC 114

相关产品: Cabotegravir | 2-Hydroxycinnamic acid | Zingibroside R1 | Maraviroc | Cyclotriazadisulfonamide hydrochloride | Erythromycin ethylsuccinate | Coronalolide | (S)-BI-1001 | Aplaviroc | Tizoxanide

相关库: Drug Repurposing Compound Library | Anti-COVID-19 Compound Library | ReFRAME Related Library | Drug-induced Liver Injury (DILI) Compound Library | Anti-Metabolism Disease Compound Library | Human Metabolite Library | Inhibitor Library | EMA Approved Drug Library | NO PAINS Compound Library | Covalent Inhibitor Library

达芦那韦 T2324信息由TargetMol中国为您提供，如您想了解更多关于达芦那韦 T2324报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途