化合物AC1NS4RE T2340

Product Introduction
Bioactivity


英文名: AC1NS4RE

描述: 是一种化学合成中的砌块

激酶实验: Competitor assay kits (green) are used to determine relative in vitro binding affinities of ARN-509 for the rat AR ligand binding domain (LBD), human progesterone receptor (PR) LBD, and full-length human estrogen receptor-alpha (ERα) and human glucocorticoid receptor (GR). Each hormone dose is performed in triplicate, relative error is calculated from the standard error of the mean (SEM), and binding curves are fit using a single binding site competition model (Prism statistical analysis software package) with R2>0.8. Experiments are conducted multiple times with SEM<0.3 log units from the average logIC50 value. Ki values are calculated as averages across experiments with SEM, and binding affinities are reported as a percentage relative to the tight-binding ligand control for that receptor[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 2.73 mg/mL (10.01 mM)


关键字: Cluster of differentiation antigen 135 | (Z)-SU5614 | CD135 | Fms like tyrosine kinase 3 | inhibit | AC-1NS4RE | FLT3 | Apoptosis | Inhibitor | AC1NS4RE

相关产品: Dodoviscin A | Noroxyhydrastinine | Buddlenoid A | Mulberroside A | Mulberroside F | Methyl rosmarinate | SU5214 | Glabrene | Mirificin | Trans-caffeic acid

相关库: ReFRAME Related Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | Apoptosis Compound Library | Protease Inhibitor Library | NO PAINS Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途