化合物5J-4 T24984
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 827001-82-1 | ¥3,723.00 | 询底价 |
10 mg | 827001-82-1 | ¥1,452.00 | 询底价 |
25 mg | 827001-82-1 | ¥2,485.00 | 询底价 |
1 mL | 827001-82-1 | ¥876.00 | 询底价 |
5 mg | 827001-82-1 | ¥968.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 5J-4
描述: 5J-4 是一种有效的钙释放激活钙通道 (CRAC) 和钙池操纵性钙内流(SOCE) 阻滞剂。 5J-4 减少 IL-17 的产生并降低 RORα 和 RORγt 的表达。
体内活性: 5J-4 (2 mg/kg; i.p.; every alternate day for 30 days) dramatically reduced the symptoms and delayed the onset of EAE and decreased the numbers of the infiltrated mononuclear cell in the CNS, and significantly decreased the population of infiltrated CD4+ population. 5J-4 reduced the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in the mouse model of inflammation[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (160.08 mM)
关键字: Inhibitor | Calcium release-activated channels | CRAC Channel | CNS | Ca2+ release-activated Ca2+ channels | 5J 4 | inflammation | 5J4 | inhibit | CD4+ cells | mononuclear cell | 5J-4 | experimental autoimmune encephalomyelitis
相关产品: Psoralenoside | HA-1004 dihydrochloride | Synta66 | Levosemotiadil | Ethosuximide | Ginsenoside Rd | ω-conotoxin MoVIA | Strontium ranelate | Gabapentin | Maresin 1
相关库: Ion Channel Inhibitor Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Metabolism Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途