化合物BPDBA T26891

Product Introduction
Bioactivity


英文名: BPDBA

描述: BPDBA 是一种有效的、具有选择性的和非竞争性的 betaine/GABA 转运体 (BGT-1) 抑制剂，对人 BGT-1 和小鼠 GAT2 具有抑制作用，IC50 分别为 20 μM 和 35 μM。

体内活性: BPDBA has good oral absorption and blood-brain barrier penetration capabilities.[1]BPDBA, a selective inhibitor of the human BGT-1 transporter with a non-competitive profile exhibiting no significant inhibitory activity at the other three human GAT subtypes. The selectivity profile of the compound was subsequently confirmed at cells expressing the four mouse GAT subtypes.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 27.5 mg/mL (75.7 mM)


关键字: BPDBA

相关产品: SCS | Cholesterol myristate | 4-Acetamidobutanoic acid | U-89843A | Cannabidivarin | Pazinaclone | Aflatrem | GABAB receptor antagonist 1 | L-DABA | Penicillin G sodium salt

相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途