化合物CJ-13,610 hydrochloride T27026L

Product Introduction
Bioactivity


英文名: CJ-13,610 hydrochloride

描述: CJ-13,610 hydrochloride 是一种具有口服活性的非氧化还原型 5-LOX 抑制剂，可用于预防 LTs 不良病理生理效应的研究。

体外活性: In intact human polymorphonuclear leukocytes (PMNL), challenged with the Ca(2+)-ionophore A23187, CJ-13,610 hydrochloride potently suppressed 5-LOX product formation with an IC50 of 70 nM. In transfected HeLa cells, CJ-13,610 hydrochloride only slightly discriminated between phosphorylatable wild-type 5-LOX and a 5-LOX mutant that lacks phosphorylation sites[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (104.66 mM)


关键字: CJ 13,610 hydrochloride | CJ13,610 hydrochloride | CJ-13,610 Hydrochloride

相关产品: 5-O-Demethylnobiletin | PGS-IN-1 | Picralinal | 4-Methyldaphnetin | PF-4191834 | ML355 | CCT365623 hydrochloride | ML351 | Xanthatin | A-69412

相关库: Bioactive Compounds Library Max | Inhibitor Library | Orally Active Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途