酚加宾 T27310

Product Introduction
Bioactivity


英文名: Fengabine

描述: Fengabine (SL-79229) 是 GABA 受体激动剂，具有抗抑郁活性，可用于治疗抑郁症。

体内活性: Fengabine (50-1000 mg/kg; i.p.) does not alter norepinephrine uptake but accelerates the turnover rate of norepinephrine in the rat brain as demonstrated by the enhancement of the alpha-methyl-p-tyrosine-induced disappearance of norepinephrine in the hypothalamus.[4]Fengabine (100 or 200 mg/kg; i.p., b.i.d.), given for 14 days, causes a desensitization of isoprenaline-stimulated adenylate cyclase in septal and cortical slices of the rat but fails to modify cortical beta, alpha-1 or alpha-2 adrenoceptor binding sites.[4]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (139.65 mM)


关键字: Fengabine

相关产品: Darigabat | Dihydroergotoxine mesylate | LAU159 | α-Thujone | Guvacine hydrobromide | Bamaluzole | (2S)-6-Prenylnaringenin | Nefiracetam | 6-Methylflavone | Nerisopam

相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途