化合物GDC0575 monohydrochloride T27407

Product Introduction
Bioactivity


英文名: GDC0575 monohydrochloride

描述: GDC0575 monohydrochloride (ARRY575) 是一种有效的、选择性的细胞周期检查点激酶 1(Chk1) 抑制剂，IC50 为 1.2 nM。GDC0575 monohydrochloride (ARRY575) 特异性结合并抑制 Chk1；这可能导致肿瘤细胞在 S 期和 G2/M 期绕过 Chk1 依赖性细胞周期停滞，从而允许细胞在进入有丝分裂之前进行 DNA 修复。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/ml (144.67 mM)


关键字: GDC-0575 Monohydrochloride | GDC 0575 Monohydrochloride | GDC0575 Monohydrochloride | GDC0575 monohydrochloride | GDC-0575 monohydrochloride | ARRY 575

相关产品: SB-218078 | M443 | CHK1-IN-2 | A-443654 | BML-277 | Rabusertib | CHK1-IN-4 hydrochloride | CHK1 inhibitor | VER-00158411 | AZD-7762

相关库: Drug Repurposing Compound Library | Anti-Cancer Drug Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Active Compound Library | DNA Damage & Repair Compound Library | Hematonosis Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途