OT-551盐酸盐 T28273L

Product Introduction
Bioactivity


英文名: OT-551 HCl

描述: OT-551 HCl 是一种 NF-Κb 抑制剂，是一种具有抗氧化特性的二取代羟胺可用于治疗白内障和老年性黄斑变性和地域性萎缩 (GA)。

体内活性: OT-551 HCl (intraperitoneally injected; rats; approximately 30 min prior to a 6 h exposure to 2700 lux white fluorescent light) significantly reduced the number of RPE cell nuclei in light-exposed eyes from water-treated animals. RPE damage index was significantly lower in the animals treated with any dose of OT-551 HCl compared to water-treated animals both in the inferior and superior hemispheres. Systemic administration of OT-551 HCl provides RPE cell protection against acute light damage.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 3.6 mg/mL (12.96 mM)


关键字: 627085-11-4 | 627085-11-4 Free base | OT-551 HCl

相关产品: Chicanine | Prunetin | 20(S)-Ginsenoside Rg3 | Stachydrine | α-Lipoic Acid | TAK-243 | 1-Caffeoylquinic acid | Polygalasaponin F | (E/Z)-IT-603 | Isoangustone A

相关库: Drug Repurposing Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Clinical Compound Library | Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途