连翘苷 T2854
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 487-41-2 | ¥486.00 | 询底价 |
25 mg | 487-41-2 | ¥987.00 | 询底价 |
5 mg | 487-41-2 | ¥366.00 | 询底价 |
100 mg | 487-41-2 | ¥1,960.00 | 询底价 |
500 mg | 487-41-2 | ¥4,830.00 | 询底价 |
10 mg | 487-41-2 | ¥598.00 | 询底价 |
50 mg | 487-41-2 | ¥1,430.00 | 询底价 |
1 mg | 487-41-2 | ¥169.00 | 询底价 |
2 mg | 487-41-2 | ¥235.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Phillyrin
描述: Phillyrin (Forsythin) 是从连翘中分离出来的一种天然产物,具有抗甲型流感病毒的活性,以及抗菌和消炎作用。
体外活性: Phillyrin suppressed high glucose-induced lipid accumulation in HepG2 cells. Phillyrin strongly inhibited high glucose-induced fatty acid synthase (FAS) expression by modulating sterol regulatory element-binding protein-1c (SREBP-1c) activation. Moreover, use of the pharmacological AMP-activated protein kinase (AMPK) inhibitor revealed that AMPK is essential for suppressing SREBP-1c expression in Phillyrin-treated cells. Liver kinase B1 (LKB1) phosphorylation is required for the Phillyrin-enhanced activation of AMPK in HepG2 hepatocytes.
体内活性: Phillyrin 对营养性肥胖小鼠具有抗肥胖作用。Phillyrin 能降低脂肪湿重(P < 0.01)、脂肪指数(P < 0.05或P < 0.01)、脂肪细胞直径及Lee指数(P < 0.05),减少空肠微绒毛面积,并降低血清甘油三酯和胆固醇水平。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 91 mg/mL(170.2 mM)
关键字: Cytochrome P450 | CYPs | Inhibitor | inhibit | Phillyrin | Influenza Virus
相关产品: CYP11B2-IN-1 | Glycycoumarin | Ayanin | Verapamil hydrochloride | alpha-Asarone | Ginsenoside C-K | 5,6,7-Trimethoxycoumarin | Isosilybin | 6',7'-Dihydroxybergamottin | CYP1B1-IN-4
相关库: Drug Repurposing Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Drug Library | Kinase Inhibitor Library | Anti-Diabetic Compound Library | Anti-Cancer Approved Drug Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library
连翘苷 T2854信息由TargetMol中国为您提供,如您想了解更多关于连翘苷 T2854报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途