化合物SCH 57790 T28722
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 221660-80-6 | ¥1,780.00 | 询底价 |
50 mg | 221660-80-6 | ¥12,900.00 | 询底价 |
5 mg | 221660-80-6 | ¥4,480.00 | 询底价 |
10 mg | 221660-80-6 | ¥6,380.00 | 询底价 |
25 mg | 221660-80-6 | ¥9,620.00 | 询底价 |
100 mg | 221660-80-6 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: SCH 57790
描述: SCH 57790 是一种新型且具有选择性的毒蕈碱 M(2) 受体拮抗剂,可释放乙酰胆碱并增强实验动物的认知能力,可用于治疗阿尔茨海默病。
体内活性: SCH 57790 (0.1-10 mg/kg; p.o.) produced dose-related increases in acetylcholine release from rat hippocampus, cortex, and striatum. SCH 57790 (0.003-1.0 mg/kg) increased retention times in young rat passive avoidance responding when given either before or after training. Also, SCH 57790 reversed scopolamine-induced deficits in mice in a passive avoidance task. In a working memory operant task in squirrel monkeys, administration of SCH 57790 (0.01-0.03 mg/kg) improved performance under a schedule of fixed-ratio discrimination with titrating delay. The effects observed with SCH 57790 in behavioral studies were qualitatively similar to the effects produced by the clinically used cholinesterase inhibitor donepezil, suggesting that blockade of muscarinic M(2) receptors is a viable approach to enhancing cognitive performance.[2]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 20 mg/mL (45.7 mM)
关键字: SCH 57790
相关产品: Promethazine | Fustin | Harmalol | NS9283 | D-Menthol | Lycorine | VU0238441 | TZ3O | Agaric acid | Dipterocarpol
相关库: Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途