化合物Z944 T29201

Product Introduction
Bioactivity


英文名: Z944

描述: Z944 是有效的 T 型钙通道拮抗剂，对跨模态和视觉识别记忆障碍有缓解作用。

体内活性: Z944 dose dependently (1, 3, 10mg/kg; i.p.) altered CMOR memory in GAERS compared to the non-epileptic control (NEC) strain. GAERS demonstrated recognition memory deficits in the visual and crossmodal variations of the CMOR task that were reversed by the highest dose of Z944. Electroencephalogram recordings determined that deficits in CMOR memory in GAERS were not the result of seizures during task performance. In contrast, NEC showed a decrease in CMOR memory following Z944 treatment[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 13 mg/ml (33.86 mM)


关键字: Ca channels | Inhibitor | Calcium Channel | Ca2+ channels | Z944 | inhibit

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相关库: Ion Channel Inhibitor Library | ReFRAME Related Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Highly Selective Inhibitor Library | Metabolism Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compound Library

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