原纤细薯蓣皂甙 T2S1749

Product Introduction
Bioactivity


英文名: Protogracillin

描述: Protogracillin 是一种甾体皂苷，分离自Dioscorea zingiberensisWright (DZW) 中。从 DZW 根状茎中获得的甾体皂苷具有抗血栓作用，同时由降低心血管疾病风险的潜力。

体外活性: Paris polyphylla J.E. Smith is extensively used in traditional systems of Indian and Chinese medicines mainly for its anticancerous property. The national and international demand for P. polyphylla is constantly increasing and most of the supplies come from wild. Illegal and unscientific exploitation coupled with habitat destruction decreases the natural population of the herb, as a consequence this species comes under vulnerable category. Restoration and conservation of the natural population of this potential herb is prerequisites. METHODS AND RESULTS: This article aims to provide an overview on chemical and biological prospective of P. polyphylla. Secondary metabolites such as daucosterol, polyphyllin D, β -ecdysterone, Paris saponins I, II, V, VI, VII, H, dioscin, oligosaccharides, heptasaccharide, octasaccharide, trigofoenoside A, Protogracillin, Paris yunnanosides G-J, padelaoside B, pinnatasterone, formosanin C and 20-hydroxyecdyson saponins have been isolated from P. polyphylla. Several biological activities such as anticancerous, antitumor, cytotoxic, anthelmintic, antimicrobial, antiangiogenic, immunostimulating, contractile and hemostatic have also been reported. CONCLUSIONS: Consequently, this review will be helpful to the researcher and scientist for further research.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 30mg/mL (28.16mM)


关键字: zingiberensis | Protogracillin | Dioscorea | Inhibitor | inhibit

相关库: Anti-Tumor Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Selected Plant-Sourced Compound Library | Chinese Pharmacopoeia Natural Product Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Miao medicine Compound Library | Traditional Mongolian Medicine Compound Library | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途