醋酸去氧皮质酮 T3033
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 56-47-3 | ¥997.00 | 询底价 |
1 mL | 56-47-3 | ¥385.00 | 询底价 |
50 mg | 56-47-3 | ¥253.00 | 询底价 |
100 mg | 56-47-3 | ¥418.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Deoxycorticosterone acetate
描述: Deoxycorticosterone acetate (Cortexone acetate) 是肾上腺产生的类固醇激素,具有盐皮质激素活性,并作为醛固酮的前体。
激酶实验: Kinase inhibition: The ability of compounds to inhibit ATR, ATM or DNAPK kinase activity istested using a radiometric-phosphate incorporation assay. A stock solution isprepared consisting of the appropriate buffer, kinase, and target peptide. To this isadded the compound of interest, at varying concentrations in DMSO to a final DMSO concentration of 7%. Assays are initiated by addition of an appropriate [γ-33P]ATP solution and incubated at 25 ℃. Assays are stopped, after the desired time course, by addition of phosphoric acid and ATP to a final concentration of 100 mM and 0.66 μM, respectively. Peptides are captured on a phosphocellulose membrane, prepared as per manufacturer's instructions, and washed six times with 200 μL of 100 mM phosphoric acid, prior to the addition of 100 μL of scintillation cocktail and scintillation counting on a 1450 Microbeta Liquid Scintillation Counter. Dose?response data are analyzed using GraphPad Prism software
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 9 mg/mL (24.2 mM)
Ethanol : 6 mg/mL (16.1 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
关键字: Deoxycorticosterone | 11-Deoxycorticosterone Acetate | Inhibitor | Cortexone Acetate | renal inflammation | Deoxycorticosterone Acetate | adrenocortin | unilateral nephrectomy | DOC | Mineralocorticoid Receptor | Endogenous Metabolite | Deoxycorticosterone acetate | DOC Acetate | 11-Deoxycorticosterone | fibrosis | Cortexone | aldosterone | precursor | glomerular injury and proteinuria | inhibit
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相关库: Anti-Neurodegenerative Disease Compound Library | Drug Repurposing Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Anti-Metabolism Disease Compound Library | GPCR Compound Library | Nuclear Receptor Compound Library | Anti-Cancer Approved Drug Library | Target-Focused Phenotypic Screening Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途