去铁他唑 T31362
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 945635-15-4 | ¥2,230.00 | 询底价 |
10 mg | 945635-15-4 | ¥3,360.00 | 询底价 |
50 mg | 945635-15-4 | ¥7,680.00 | 询底价 |
1 mg | 945635-15-4 | ¥910.00 | 询底价 |
25 mg | 945635-15-4 | ¥5,480.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Deferitazole
描述: Deferitazole (FBS 0701) 是一种新型且具有口服活性、选择性和高亲和力的铁螯合剂。
体外活性: Deferitazole (FBS0701) displays a high affinity and selectivity for iron(III) as demonstrated by the log β2 = 33.39 ± 0.03 and the pFe(3+) value of 22.3. Two equilibrating isomeric forms of the iron(III) complex exist under biological conditions. Deferitazole also binds the trivalent metals Al(III) and La(III) with high affinity; log β2 values, 26.68 and 21.55 respectively. The affinity of Deferitazole for divalent cations is somewhat lower, with the exception of Cu(II) which possesses a log β2 value of 25.5; Deferitazole scavenges iron from labile sources such as citrate and albumin with efficiencies comparable with those of other therapeutic iron chelators, including deferasirox, deferiprone and desferrioxamine. The Fe(III)(Deferitazole)2 is stable under physiological conditions and does not redox cycle. The high affinity of Deferitazole for iron(III) renders it unlikely that this chelator will lead to the redistribution of iron and consequently Deferitazole shows considerable promise as a therapeutic iron(III) chelator.[1]
存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Deferitazole
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途