化合物Rapastinel acetate T3407L

Product Introduction
Bioactivity


英文名: Rapastinel acetate

描述: Rapastinel acetate 是 N-甲基-D-天冬氨酸 (NMDA) 受体的调节剂和甘氨酸位点的部分激动剂，具有长效抗抑郁作用。

体内活性: Rapastinel acetate (3mg/kg; i.v.) facilitated long-term potentiation (LTP) 1day-2weeks but not 4weeks post-dosing. Biweekly dosing with Rapastinel acetate sustained this effect for at least 8weeks. A single dose of Rapastinel acetate increased the proportion of whole-cell NMDAR current contributed by NR2B-containing NMDARs in the hippocampus 1week post-dosing, which returned to baseline by 4weeks post-dosing[1].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 22.5 mg/mL (47.52 mM)


关键字: 117928-94-6 | Rapastinel Acetate | 117928-94-6 Free base

相关产品: Glypromate | O-Phospho-L-serine | DL-AP5 | 7-Chlorokynurenic acid | Bupivacaine hydrochloride monohydrate | Quininic acid | ZL006 | S1R agonist 2 | cis-PDA | Co 101244 hydrochloride

相关库: Neurotransmitter Receptor Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Antidepressant Compound Library | Peptide Compound Library | Anti-Cancer Clinical Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途