化合物ST-1006 T34709

Product Introduction
Bioactivity


英文名: ST-1006

描述: ST-1006是一种强效组胺 H4受体激动剂（pKi：7.94）。ST-1006具有抗炎作用。ST-1006是一种有效的嗜碱性粒细胞迁移诱导剂，可诱导嗜碱性粒细胞迁移。 ST-1006 具有抗炎作用和止痒作用。

体外活性: ST-1006 (10 μM) is an effective inducer of eosinophil migration, promoting eosinophil migration [3].ST-1006 (0-100 μM) inhibits FceRI-mediated eosinophil activation and reduces the expression levels of CD63 and CD203c in activated eosinophils through FceRI activation [3].

体内活性: ST-1006 (1-100 mg/kg; s.c.; male CD-1 mice) exhibits anti-inflammatory and anti-itch properties [5].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 3.67 mg/mL (10 mM)


关键字: ST-1006 | ST1006

相关产品: Thioperamide maleate | Hydroxyzine Pamoate | 2-Pyridylethylamine dihydrochloride | Alginic acid | LML134 | Doxepin D3 Hydrochloride | Pheniramine maleate | Niaprazine | Amodiaquine dihydrochloride dihydrate | Famotidine

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | GPCR Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途