Osteocalcin (1-49) (human) (trifluoroacetate salt) T35604

Product Introduction
Bioactivity


英文名: Osteocalcin (1-49) (human) (trifluoroacetate salt)

描述: Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women.

体外活性: In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Formic Acid : 1 mg/mL


关键字: Osteocalcin (1 49) (human) (trifluoroacetate salt) | Osteocalcin (149) (human) (trifluoroacetate salt) | Osteocalcin

Osteocalcin (1-49) (human) (trifluoroacetate salt) T35604信息由TargetMol中国为您提供，如您想了解更多关于Osteocalcin (1-49) (human) (trifluoroacetate salt) T35604报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途