Cytostatin (sodium salt) T35613

Product Introduction
Bioactivity


英文名: Cytostatin (sodium salt)

描述: Cytostatin (sodium salt) is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 μg/ml). Cytostatin (sodium salt) potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Methanol : Soluble
H2O : Soluble
DMSO : Soluble


关键字: Cytostatin (sodium salt) | Cytostatin

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途