Quinacrine analog 34 T35747

Product Introduction
Bioactivity


英文名: Quinacrine analog 34

描述: Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels of the autophagy biomarker LC3-II and to induce lysosome deacidification.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mg/mL
DMSO:PBS (pH 7.2) (1:1) : 0.5 mg/mL
Ethanol : 5 mg/mL
DMF : 10 mg/mL


关键字: Quinacrine analog 34

Quinacrine analog 34 T35747信息由TargetMol中国为您提供，如您想了解更多关于Quinacrine analog 34 T35747报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途