ZLY032 T35816
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 2314465-67-1 | ¥6,350.00 | 询底价 |
10 mg | 2314465-67-1 | ¥1,470.00 | 询底价 |
5 mg | 2314465-67-1 | ¥770.00 | 询底价 |
25 mg | 2314465-67-1 | ¥3,370.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ZLY032
描述: ZLY032 is a dual agonist of free fatty acid receptor 1 (FFAR1/GPR40; EC50= 68 nM in a FLIPR assay) and peroxisome proliferator-activated receptor δ (PPARδ; EC50= 102 nM in a reporter assay).1It is selective for FFAR1 and PPARδ over PPARα and PPARγ (EC50s = >10 μM for both). ZLY032 (40 mg/kg, twice per day) reduces blood glucose levels in an oral glucose tolerance test and decreases plasma total cholesterol and triglyceride levels in theob/obmouse model of metabolic disease.2It reduces hepatic steatosis and plasma alanine transaminase (ALT) and aspartate aminotransferase (AST) levels in a mouse model of non-alcoholic steatohepatitis (NASH) induced by a methionine and choline-deficient diet at the same dose.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO:PBS (pH 7.2) (1:5) : 0.16 mg/mL
DMSO : 30 mg/mL
DMF : 30 mg/mL
关键字: ZLY 032 | ZLY032 | ZLY-032
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途