PB2 T35889
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 914940-24-2 | ¥1,660.00 | 询底价 |
10 mg | 914940-24-2 | ¥2,890.00 | 询底价 |
1 mL | 914940-24-2 | ¥1,830.00 | 询底价 |
2 mg | 914940-24-2 | ¥984.00 | 询底价 |
25 mg | 914940-24-2 | ¥5,940.00 | 询底价 |
Product Introduction
Bioactivity
英文名: PB2
描述: PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficacy in promoting RGC survival. Notably, PB2 exhibits superior permeability compared to TCEP. Serving as a potent reducing agent, PB2 provides robust neuroprotection for RGCs[1].
体外活性: PB2 (0.001~100000 nM; 72 hours; RGCs) increases RGC viability[1].PB2 has modifications that neutralize the polarity of the compounds. The methylesters of PB2 is likely to be cleaved by cytosolic esterases, yielding a polar intracellular intermediate that would be unlikely to cross cell membranes[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 100 mg/mL (349.52 mM)
关键字: PB2 | PB 2 | PB-2
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途