N-Arachidonoyl Taurine T35918

Product Introduction
Bioactivity


英文名: N-Arachidonoyl Taurine

描述: N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of δ9-tetrahydrocannabinol (δ9-THC).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMF : 10 mg/mL
DMSO : 20 mg/mL
PBS (pH 7.2) : 1.5 mg/mL


关键字: NArachidonoyl Taurine | N-Arachidonoyl Taurine | N Arachidonoyl Taurine

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途