PAR2 (1-6) amide (human) (trifluoroacetate salt) T35955

Product Introduction
Bioactivity


英文名: PAR2 (1-6) amide (human) (trifluoroacetate salt)

描述: PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 5 mg/mL
DMF : 30 mg/mL
DMSO : 15 mg/mL
PBS (pH 7.2) : 10 mg/mL


关键字: PAR2 (16) amide (human) (trifluoroacetate salt) | PAR-2 (1-6) amide (human) (trifluoroacetate salt) | PAR 2 | PAR2 (1 6) amide (human) (trifluoroacetate salt) | PAR2 Amide | PAR-2 | PAR2

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途