12(R)-HETE T36145

Product Introduction
Bioactivity


英文名: 12(R)-HETE

描述: Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid . In mammals, 12(R)-HETE can be produced by 12(R)-LOs and also by CYP450 oxidation. The activity of 12(R)-HETE in mammals is predominantly proinflammatory. 12(R)-HETE exhibits dose-dependent leukocyte chemotaxis at concentrations as low as 100 nM, and lowers intraocular pressure in rabbits.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : Miscible
DMSO : Miscible
PBS (pH 7.2) : 0.8 mg/mL
DMF : Miscible
0.1 M Na2CO3 : 2 mg/mL


关键字: 12(R)HETE | 12HETE | 12(R) HETE

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途