8-iso Prostaglandin E2 T36160

Product Introduction
Bioactivity


英文名: 8-iso Prostaglandin E2

描述: 8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 μM, respectively. When infused into the renal artery of the rat at a concentration of 4 μg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: PBS (pH 7.2) : >5 mg/mL (from PGE2)
DMSO : >100 mg/mL (from PGE2)
Ethanol : >100 mg/mL (from PGE2)
DMF : >100 mg/mL (from PGE2)


关键字: 8 iso Prostaglandin E2 | 8-iso Prostaglandin E-2 | 8iso Prostaglandin E2

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途