AZD 1152 (hydrochloride) T36199
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 722543-50-2 | ¥437.00 | 询底价 |
5 mg | 722543-50-2 | ¥1,970.00 | 询底价 |
25 mg | 722543-50-2 | ¥4,370.00 | 询底价 |
10 mg | 722543-50-2 | ¥2,620.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AZD 1152 (hydrochloride)
描述: AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO:PBS(pH 7.2) (1:4) : 0.2 mg/mL
DMSO : 1 mg/mL
关键字: AZD 1152 | AZD1152 | AZD-1152 | AZD 1152 (hydrochloride)
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途